YWHAB Antibody - Cat. #: CSB-PA981536

SKU: CSB-PA981536

Size :100ul

Clone Number:

Aliases:14 3 3 antibody; 14 3 3 protein beta antibody; 14 3 3 protein beta/alpha antibody; 14 3 3 protein zeta antibody; 14 3 3 zeta antibody; 14-3-3 protein beta/alpha antibody; 14-3-3 protein/cytosolic phospholipase A2 antibody; 1433B_HUMAN antibody; GW128 antibody; HS1 antibody; KCIP 1 antibody; KCIP-1 antibody; MGC111427 antibody; MGC126532 antibody; MGC138156 antibody; N-terminally processed antibody; Protein 1054 antibody; Protein kinase C inhibitor protein 1 antibody; Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein; delta polypeptide antibody; Tyrosine 3/tryptophan 5 -monooxygenase activation protein; zeta polypeptide antibody; YWHAB antibody; YWHAD antibody; YWHAZ antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P31946

Immunogen:Synthesized peptide derived from internal of Human 14-3-3 ?.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2.

Leffers H., J. Mol. Biol. 231:982-998(1993).
Deloukas P., Nature 414:865-871(2001).
Gevaert K., Nat. Biotechnol. 21:566-569(2003).
Chi A., J. Proteome Res. 5:3135-3144(2006).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:YWHAB

Research Areas:Neuroscience;Cell biology;Signal transduction?Stem cells