WDR34 Antibody - Cat. #: CSB-PA842668LA01HU

SKU: CSB-PA842668LA01HU

Size :50ug

Clone Number:

Aliases:bA216B9.3 antibody; DIC5 antibody; MGC20486 antibody; OTTHUMP00000022282 antibody; RP11 216B9.5 antibody; WD repeat containing protein 34 antibody; WD repeat domain 34 antibody; WD repeat-containing protein 34 antibody; WDR 34 antibody; Wdr34 antibody; WDR34_HUMAN antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q96EX3

Immunogen:Recombinant Human WD repeat-containing protein 34 protein (1-210AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Background:Critical for ciliary functions, essential to normal development and survival, most probably as a previously unrecognized component of the mammalian dynein-motor-based intraflagellar transport (IFT) machinery. Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Inhibits the MAP3K7-induced NF-kappa-B activation pathway. Inhibits MAP3K7 phosphorylation at \\\'Thr-184\\\' and \\\'Thr-187\\\' upon Il-1 beta stimulation.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:WDR34

Research Areas:Immunology; Signal transduction