VPS8 antibody , Cat. # FNab09451

SKU: FNab09451

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Plays a role in vesicle-mediated protein trafficking of the endocytic membrane transport pathway. Believed to act as a component of the putative CORVET endosomal tethering complexes which is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations(PubMed:25266290). Functions predominantly in APPL1-containing endosomes(PubMed:25266290).

Immunogen:vacuolar protein sorting 8 homolog(S. cerevisiae)

Synonyms:FLJ32099, KIAA0804, VPS8

Observed MW:151 kDa

Uniprot ID:Q8N3P4

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IF,IP

Recommended dilution:WB: 1:500-1:5000?IP: 1:200-1:2000; IF: 1:10-1:100

Gene ID:23355

Research Area:Signal Transduction