VPP2 Polyclonal Antibody

SKU: BT-AP15499

Size:100μL

Background:The protein encoded by this gene is a subunit of the vacuolar ATPase (v-ATPase), an heteromultimeric enzyme that is present in intracellular vesicles and in the plasma membrane of specialized cells, and which is essential for the acidification of diverse cellular components. V-ATPase is comprised of a membrane peripheral V(1) domain for ATP hydrolysis, and an integral membrane V(0) domain for proton translocation. The subunit encoded by this gene is a component of the V(0) domain. Mutations in this gene are a cause of both cutis laxa type II and wrinkly skin syndrome.

Research_area:Signal transduction; Metabolism

Target_protein:ATP6V0A2

applications:WB, ELISA

Reactivity:Human, Rat, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:V-type proton ATPase 116 kDa subunit a isoform 2

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: Q9Y487; Mouse: P15920

Synonyms:V-type proton ATPase 116 kDa subunit a isoform 2 ;V-ATPase 116 kDa isoform a2;Lysosomal H;+-transporting ATPase V0 subunit a2;TJ6;Vacuolar proton translocating ATPase 116 kDa subunit a isoform

GeneID:Human: 23545