VAMP2 Monoclonal Antibody

SKU: BT-MCA4244

Size:100μL

Background:The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin. It is a likely candidate gene for familial infantile myasthenia (FIMG) because of its map location and because it encodes a synaptic vesicle protein of the type that has been implicated in the pathogenesis of FIMG.

Research_area:Others

Target_protein:VAMP2

applications:IHC, FCM

Reactivity:Human, Mouse, Monkey, Rat

Clonality:Monoclonal

Clone ID:5A2C7

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:VAMP2

Immunogen:Purified recombinant fragment of human VAMP2 (AA: 2-89aa) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):12.7kDa

UniProt accession:P63027

Synonyms:SYB2, VAMP-2, NEDHAHM

GeneID:6844