USP18 antibody , Cat. # FNab09313

SKU: FNab09313

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Can efficiently cleave only ISG15 fusions including native ISG15 conjugates linked via isopeptide bonds. Necessary to maintain a critical cellular balance of ISG15-conjugated proteins in both healthy and stressed organisms. Isoform 2: Has enzymatic activity similar to isoform 1 and interferes with type I interferon signaling. Major deISGylation enzyme for nuclear proteins(PubMed:22170061).

Immunogen:ubiquitin specific peptidase 18

Synonyms:43 kDa ISG15 specific protease, hUBP43, ISG43, Ubl thiolesterase 18, UBP43, USP18

Observed MW:70 kDa, 43 kDa

Uniprot ID:Q9UMW8

Reactivity:Human

Tested Application:ELISA, WB

Recommended dilution:WB: 1:500-1:1000

Gene ID:11274

Research Area:Epigenetics, Metabolism