USP12 Polyclonal Antibody

SKU: E-AB-18513

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: USP12

Target Synonym: Deubiquitinating enzyme 12;OTTHUMP00000042337;UBH 1;UBH1;Ubiquitin carboxyl terminal hydrolase 12;Ubiquitin carboxyl-terminal hydrolase 12;Ubiquitin hydrolyzing enzyme 1 ;Ubiquitin specific peptidase 12;Ubiquitin specific processing protease 12;Ubiquitin specific protease 12 like 1;Ubiquitin thioesterase 12;Ubiquitin thiolesterase 12;Ubiquitin-hydrolyzing enzyme 1;Ubiquitin-specific-processing protease 12;UBP12;USP 12;Usp12;USP12L1

Research Areas: Cell Biology;Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: O75317

Accession:

Background: The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. Through the use of a wide range of enzymes that can add or remove ubiquitin, the Ub pathway controls many intracellular processes such as signal transduction, transcriptional activation and cell cycle progression. USP12 (ubiquitin specific peptidase 12), also known as UBH1 or USP12L1, is a 370 amino acid protein belonging to the peptidase C19 family and the USP12/USP46 subfamily. Considered a deubiquitinating enzyme, it is suggested that USP12 has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have high activity. The gene encoding USP12 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome.

Concentration: 0.6 mg/mL

Immunogen: Full length fusion protein

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: WB 1:500-1:2000;IHC 1:25-1:100

Calculated MW: 43 kDa

ObservedMW: Refer to figures