UBR2 Antibody - Cat. #: CSB-PA809001LA01HU

SKU: CSB-PA809001LA01HU

Size :50ug

Clone Number:

Aliases:UBR2 antibody; C6orf133 antibody; KIAA0349 antibody; E3 ubiquitin-protein ligase UBR2 antibody; EC 2.3.2.27 antibody; N-recognin-2 antibody; RING-type E3 ubiquitin transferase UBR2 antibody; Ubiquitin-protein ligase E3-alpha-2 antibody; Ubiquitin-protein ligase E3-alpha-II antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q8IWV8

Immunogen:Recombinant Human E3 ubiquitin-protein ligase UBR2 protein (101-439AA)

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB; Recommended dilution: WB:1:1000-1:5000

Background:E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Plays a critical role in chromatin inactivation and chromosome-wide transcriptional silencing during meiosis via ubiquitination of histone H2A. Binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:UBR2

Research Areas:Cell biology