UBE2K Polyclonal Antibody

SKU: BT-AP15300

Size:100μL

Background:The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene.

Research_area:Epigenetics and nuclear signaling; Cell biology; Neuroscience

Target_protein:UBE2K

applications:WB, ELISA

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Ubiquitin-conjugating enzyme E2 K

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: P61086; Mouse: P61087

Synonyms:Ubiquitin-conjugating enzyme E2 K ;EC 6.3.2.19;Huntingtin-interacting protein 2;HIP-2;Ubiquitin carrier protein;Ubiquitin-conjugating enzyme E2-25 kDa;Ubiquitin-conjugating enzyme E2;25K;

GeneID:Human: 3093