UBE2C Monoclonal Antibody

SKU: BT-MCA4491

Size:100μL

Background:The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is required for the destruction of mitotic cyclins and for cell cycle progression, and may be involved in cancer progression. Multiple transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene have been defined on chromosomes 4, 14, 15, 18, and 19.

Research_area:Others

Target_protein:UBE2C

applications:IHC

Reactivity:Human

Clonality:Monoclonal

Clone ID:1F5D3

Host:Mouse

Isotype:Mouse IgG2a

Gene Symbol/ Name:UBE2C

Immunogen:Purified recombinant fragment of human UBE2C (AA: FULL(1-179)) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide.

Concentration:

Molecular weight(Da):19.7kDa

UniProt accession:O00762

Synonyms:UBCH10, dJ447F3.2

GeneID:11065