TyrRS rabbit pAb

SKU: ES8516

Size: 100μL

Source:Rabbit

Applications:WB;IHC;ELISA

Reactivity:Human;Mouse;Rat

Dilution:WB 1:500-2000,IHC 1:50-300 ELISA 1:10000-20000

Immunogen:The antiserum was produced against synthesized peptide derived from the C-terminal region of human YARS. AA range:451-500

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):60kD

Human_gene_id:8565

Human_swiss_prot_no:P54577

Subcellular_location:Cytoplasm .

Other_name:Tyrosine--tRNA ligase, cytoplasmic (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS)

Background:Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine. [provided by RefSeq, Jul 2008],