TSC1 Antibody, FITC conjugated - Cat. #: CSB-PA849764LC01HU

SKU: CSB-PA849764LC01HU

Size :50ug

Clone Number:

Aliases:Hamartin antibody; kiaa0243 antibody; LAM antibody; TSC antibody; Tsc1 antibody; Tsc1 gene antibody; TSC1_HUMAN antibody; Tuberous sclerosis 1 antibody; Tuberous sclerosis 1 protein antibody; tumor suppressor antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q92574

Immunogen:Recombinant Human Hamartin protein (101-344AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:

Background:In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:TSC1

Research Areas:Epigenetics and Nuclear Signaling; Cancer; Cell biology; Metabolism