TRPV5 antibody , Cat. # FNab09029

SKU: FNab09029

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Constitutively active calcium selective cation channel thought to be involved in Ca(2+) reabsorption in kidney and intestine(PubMed:11549322, PubMed:18768590). Required for normal Ca(2+) reabsorption in the kidney distal convoluted tubules(By similarity). The channel is activated by low internal calcium level and the current exhibits an inward rectification(PubMed:11549322, PubMed:18768590). A Ca(2+)-dependent feedback regulation includes fast channel inactivation and slow current decay(By similarity). Heteromeric assembly with TRPV6 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating(By similarity).

Immunogen:transient receptor potential cation channel, subfamily V, member 5

Synonyms:Calcium transport protein 2, CAT2, ECaC, ECAC1, Epithelial calcium channel 1, Osm 9 like TRP channel 3, OTRPC3, TRPV5

Observed MW:43 kDa

Uniprot ID:Q9NQA5

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, IF

Recommended dilution:IF: 1:10-1:100

Gene ID:56302

Research Area:Epigenetics, Metabolism