TRPC4AP Polyclonal Antibody

SKU: E-AB-17161

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: TRPC4AP

Target Synonym: C20orf188; TRPC4AP;Chromosome 20 open reading frame 188;Protein TAP1;Protein TRUSS;Short transient receptor potential channel 4 associated protein;Short transient receptor potential channel 4-associated protein;TAP1 protein;TNF receptor ubiquitous scaffolding/signaling protein;TNF-receptor ubiquitous scaffolding/signaling protein;TP4AP;Transient receptor potential cation channel;subfamily C;member 4 associated protein;Trp4 associated protein;Trp4-associated protein;Trpc4 associated protein;Trpc4-associated protein;TRPC4AP;TRRP4AP;TRUSS;Tumor necrosis factor receptor-associated ubiquitous scaffolding and signaling protein

Research Areas: Epigenetics and Nuclear Signaling;Signal transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q8TEL6

Accession:

Background: TRPC4AP (transient receptor potential cation channel, subfamily C, member 4 associated protein), also known as TRUSS or TRRP4AP, is a 797 amino acid protein that is expressed in a variety of tissues, with highest expression in liver, heart, testis and brain. Thought to function as a scaffolding protein, TRPC4AP interacts with TNF-R1 and may both link TNF-R1 to the IKK signalsome complex, and participate in the activation of NFκB p50, an event that occurs in response to TNF-R1 ligation. TRPC4AP exists as multiple alternatively spliced isoforms that are encoded by a gene whicHuman, Mouseaps to human chromosome 20. Comprising approximately 2% of the human genome, chromosome 20 contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome.

Concentration: 0.9 mg/mL

Immunogen: Fusion protein of human TRPC4AP

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: IHC 1:30-150

Calculated MW:

ObservedMW: