TRPC4AP antibody , Cat. # FNab09016

SKU: FNab09016

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Substrate-specific adapter of a DCX(DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. The DCX(TRUSS) complex specifically mediates the polyubiquitination and subsequent degradation of MYC. Also participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome. Involved in JNK activation via its interaction with TRAF2. Also involved in elevation of endoplasmic reticulum Ca(2+) storage reduction in response to CHRM1.

Immunogen:transient receptor potential cation channel, subfamily C, member 4 associated protein

Synonyms:C20orf188, Protein TAP1, Protein TRUSS, Trp4 associated protein, Trpc4 associated protein, TRPC4AP, TRRP4AP, TRUSS

Observed MW:91 kDa

Uniprot ID:Q8TEL6

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, IP, IHC, WB

Recommended dilution:WB: 1:200-1:1000; IP: 1:200-1:1000; IHC: 1:20-1:200

Gene ID:26133

Research Area:Signal Transduction