TRIP4 antibody , Cat. # FNab08998

SKU: FNab08998

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Transcription coactivator which associates with nuclear receptors, transcriptional coactivators including EP300, CREBBP and NCOA1, and basal transcription factors like TBP and TFIIA to facilitate nuclear receptors-mediated transcription. May thereby play an important role in establishing distinct coactivator complexes under different cellular conditions. Plays a role in thyroid hormone receptor and estrogen receptor transactivation(PubMed:10454579, PubMed:25219498). Also involved in androgen receptor transactivation(By similarity). Plays a pivotal role in the transactivation of NF-kappa-B, SRF and AP1. Acts as a mediator of transrepression between nuclear receptor and either AP1 or NF-kappa-B(PubMed:12077347). May play a role in the development of neuromuscular junction(PubMed:26924529).

Immunogen:thyroid hormone receptor interactor 4

Synonyms:TRIP4, TRIP 4, TR interacting protein 4, ASC 1, HsT17391

Observed MW:66 kDa

Uniprot ID:Q15650

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB

Recommended dilution:WB: 1:500-1:5000

Gene ID:9325

Research Area:Metabolism