TRADD Monoclonal Antibody

SKU: BT-MCA4457

Size:100μL

Background:The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq, Jul 2008]

Research_area:Cell Biology

Target_protein:TRADD

applications:FCM

Reactivity:

Clonality:Monoclonal

Clone ID:3A1E8

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:TRADD

Immunogen:Purified recombinant fragment of human TRADD (AA: 1-177) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):34.2kDa

UniProt accession:Q15628

Synonyms:Hs.89862

GeneID:8717