TNFRSF13C Antibody - Cat. #: CSB-PA249091

SKU: CSB-PA249091

Size :50ul

Clone Number:

Aliases:B cell activating factor receptor antibody; B-cell-activating factor receptor antibody; BAFF R antibody; BAFF receptor antibody; BAFF-R antibody; BAFFR antibody; BLyS receptor 3 antibody; BlySR3 antibody; BR 3 antibody; BR3 antibody; BROMIX antibody; CD 268 antibody; CD268 antibody; CD268 antigen antibody; CVID4 antibody; MGC138235 antibody; OTTHUMP00000028746 antibody; Prolixin antibody; TNFRSF 13C antibody; Tnfrsf13c antibody; TR13C_HUMAN antibody; Tumor necrosis factor receptor subunit member 13C antibody; Tumor necrosis factor receptor superfamily member 13C antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q96RJ3

Immunogen:Synthetic peptide of Human TNFRSF13C

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:50-1:200

Background:B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:TNFRSF13C

Research Areas:Signal transduction