TNFRSF10A Antibody - Cat. #: CSB-PA199651

SKU: CSB-PA199651

Size :100ul

Clone Number:

Aliases:Apo2 antibody; CD261 antibody; Cytotoxic TRAIL receptor antibody; Death receptor 4 antibody; DR4 antibody; NF related apoptosis-inducing ligand receptor 1 antibody; TNF receptor superfamily member 10a antibody; TNF-related apoptosis-inducing ligand receptor 1 antibody; TNFRSF10A antibody; TR10A_HUMAN antibody; TRAIL receptor 1 antibody; TRAIL-R1 antibody; TRAILR 1 antibody; TRAILR1 antibody; Tumor necrosis factor receptor superfamily member 10A antibody; Tumor necrosis factor receptor superfamily member 10a variant 2 antibody; Tumor necrosis factor receptor superfamily; member 10a antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O00220

Immunogen:Synthesized peptide derived from C-terminal of Human TR10A.

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B.

Pan G., Science 276:111-113(1997).
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Chaudhary P.M., Immunity 7:821-830(1997).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:TNFRSF10A

Research Areas:Cardiovascular?Cell biology;Immunology