TNF α Mouse mAb

SKU: EM1197

Size: 100μL

Source:Mouse

Applications:WB, IHC

Reactivity:Human, Rat, Mouse

Dilution:WB 1:1,000-2,000 IHC 1:50

Immunogen:Synthetic Peptide

Storage_stability:PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality:Monoclonal

Isotype:IgG1

Concentration:1mg/mL

Observed_band(KD):17,25kDa

Human_gene_id:7124

Human_swiss_prot_no:P01375

Subcellular_location:Secreted,Cell membrane

Other_name:APC1 antibody, DIF antibody, TNFSF2 antibody, Tumor necrosis factor alpha antibody

Background:TNF-α, the prototypical member of the TNF protein superfamily, is a homotrimeric type-II membrane protein. It can cause cytolysis of certain tumor cell lines; it is involved in the induction of cachexia; it is a potent pyrogen, causing fever by direct action or by stimulation of interlerukin-1 secretion; it can stimulate cell proliferation and induce cell differentiation under certain conditions..