TLE2 Antibody - Cat. #: CSB-PA206010

SKU: CSB-PA206010

Size :100ul

Clone Number:

Aliases:enhancer of split groucho 2 antibody; enhancer of split groucho 2 antibody; Enhancer of split groucho-like protein 2 antibody; ESG antibody; ESG2 antibody; FLJ41188 antibody; GRG2 antibody; Groucho2 antibody; KIAA4188 antibody; MGC124808 antibody; mKIAA4188 antibody; Tle2 antibody; Tle2 protein antibody; TLE2_HUMAN antibody; transducin like enhancer of split 2 antibody; Transducin like enhancer of split 2, homolog of Drosophila E(sp1) antibody; Transducin like enhancer protein 2 antibody; Transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila) antibody; Transducin-like enhancer of split 2, homolog of Drosophila E(spl) antibody; Transducin-like enhancer protein 2 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q04725

Immunogen:Synthesized peptide derived from internal of Human TLE2.

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES By similarity.

Stifani S., Nat. Genet. 2:119-127(1992).
Grimwood J., Nature 428:529-535(2004).
Grbavec D., Eur. J. Biochem. 258:339-349(1998).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:TLE2

Research Areas:Epigenetics and Nuclear Signaling