TFAP2A Antibody - Cat. #: CSB-PA178989

SKU: CSB-PA178989

Size :100ul

Clone Number:

Aliases:Activating enhancer binding protein 2 alpha antibody; Activating enhancer-binding protein 2-alpha antibody; Activator protein 2 antibody; AP 2 transcription factor antibody; AP 2alpha antibody; AP-2 antibody; AP-2 transcription factor antibody; AP2 antibody; AP2 Transcription Factor antibody; AP2-alpha antibody; AP2A_HUMAN antibody; AP2TF antibody; BOFS antibody; FLJ51761 antibody; TFAP 2 antibody; TFAP 2A antibody; TFAP2 antibody; TFAP2A antibody; Transcription factor AP 2 alpha (activating enhancer binding protein 2 alpha) antibody; Transcription factor AP-2-alpha antibody; Transcription factor AP2 alpha antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P05549

Immunogen:Synthesized peptide derived from Human AP-2.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB, IHC; WB:1:500-1:3000, IHC:1:50-1:100

Background:Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region.

ShunJiang Yu, J. Biol. Chem., May 2003; 278: 19597 - 19602.
TT Chen, Mol. Cell. Biol., Jun 1997; 17: 3056 - 3064.
Oscar B. Goodman, J. Biol. Chem., Oct 1995; 270: 23768.
Didier Jean, J. Biol. Chem., Jun 1998; 273: 16501

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:TFAP2A

Research Areas:Epigenetics and Nuclear Signaling