TDRD1 Antibody, Biotin conjugated - Cat. #: CSB-PA874834LD01HU

SKU: CSB-PA874834LD01HU

Size :50ug

Clone Number:

Aliases:Cancer/testis antigen 41.1 antibody; CT41.1 antibody; FLJ21082 antibody; MTR 1 antibody; TDRD 1 antibody; tdrd1 antibody; TDRD1_HUMAN antibody; Tudor domain containing 1 antibody; Tudor domain containing protein 1 antibody; Tudor domain-containing protein 1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9BXT4

Immunogen:Recombinant Human Tudor domain-containing protein 1 protein (12-314AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Plays a central role during spermatogenesis by participating in the repression transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Required for the localization of Piwi proteins to the meiotic nuage. Involved in the piRNA metabolic process by ensuring the entry of correct transcripts into the normal piRNA pool and limiting the entry of cellular transcripts into the piRNA pathway. May act by allowing the recruitment of piRNA biogenesis or loading factors that ensure the correct entry of transcripts and piRNAs into Piwi proteins (By similarity).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:TDRD1

Research Areas:Developmental biology