TCF7 Polyclonal Antibody

SKU: E-AB-53275

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:TCF7

Target Synonym:FLJ36364;MGC47735;OTTHUMP00000159391;T cell factor 1;T cell specific transcription factor 1;T-cell factor 1;T-cell-specific transcription factor 1;TCF-1;TCF-7;TCF1;Tcf7;TCF7 transcription factor 7;TCF7;Transcription factor 7 (T cell specific HMG box);Transcription factor 7;Transcription factor-7;T-cell specific;Transcription factor-7;T-cell specific;1

Research Areas:Epigenetics and Nuclear Signaling;Immunology;Stem Cells

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse

Application:IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P36402

Accession:

Background:This gene encodes a member of the T-cell factor/lymphoid enhancer-binding factor family of high mobility group (HMG) box transcriptional activators. This gene is expressed predominantly in T-cells and plays a critical role in natural killer cell and innate lymphoid cell development. The encoded protein forms a complex with beta-catenin and activates transcription through a Wnt/beta-catenin signaling pathway. Mice with a knockout of this gene are viable and fertile, but display a block in T-lymphocyte differentiation. Alternative splicing results in multiple transcript variants. Naturally-occurring isoforms lacking the N-terminal beta-catenin interaction domain may act as dominant negative regulators of Wnt signaling.

Concentration:0.78 mg/mL

Immunogen:Synthetic peptide of human TCF7

Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method:Antigen affinity purification

Dilution:IHC 1:40-1:200

Calculated MW:

ObservedMW: