TCF4 Polyclonal Antibody

SKU: E-AB-60206

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:TCF4

Target Synonym:TCF4;E2-2;FECD3;ITF-2;ITF2;PTHS;SEF-2;SEF2;SEF2-1;SEF2-1A;SEF2-1B;SEF2-1D;TCF-4;bHLHb19;TCF4

Research Areas:Cancer;Epigenetics and Nuclear Signaling;Stem Cells

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IF

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P15884

Accession:

Background:This gene encodes transcription factor 4, a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. In addition, an intronic CTG repeat normally numbering 10-37 repeat units can expand to >50 repeat units and cause Fuchs endothelial corneal dystrophy. Multiple alternatively spliced transcript variants that encode different proteins have been described.

Concentration:1mg/mL

Immunogen:Recombinant fusion protein of human TCF4 (NP_001077431.1).

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification method:Affinity purification

Dilution:WB 1:500-1:2000;IF 1:50-1:200

Calculated MW:48-71kDa

ObservedMW:60kDa