Survivin Polyclonal Antibody

SKU: BT-AP01683

Size:100μL

Background:This gene is a member of the inhibitor of apoptosis (IAP) gene family| which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains| but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors| yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Research_area:Cancer; Cell biology; Neuroscience; Epigenetics and nuclear signaling

Target_protein:BIRC5

applications:WB, IHC-p, IF, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Baculoviral IAP repeat-containing protein 5

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):16389

UniProt accession:Human: O15392; Mouse: O70201; Rat: Q9JHY7

Synonyms:Baculoviral IAP repeat-containing protein 5; BIRC5; API4; IAP4; Baculoviral IAP repeat-containing protein 5; Apoptosis inhibitor 4; Apoptosis inhibitor survivin

GeneID:Human: 332; Mouse: 11799; Rat: 64041