STRAB Rabbit Polyclonal Antibody

SKU: BT-AP12887

Size:100μL

Background:This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered| and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11| a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm| and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein| and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes| located on chromosomes 1 and 7| have been found for this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Research_area:Signal transduction; Metabolism; Cell biology

Target_protein:STRADB

applications:WB

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:STRAB

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):45980

UniProt accession:Human: Q9C0K7; Mouse: Q8K4T3

Synonyms:STRAB

GeneID:Human: 55437; Mouse: 227154