STEAP1 Antibody - Cat. #: CSB-PA13354A0Rb

SKU: CSB-PA13354A0Rb

Size :50ug

Clone Number:

Aliases:2410007B19Rik antibody; EC 1.16.1.- antibody; Metalloreductase STEAP1 antibody; MGC19484 antibody; PRSS 24 antibody; PRSS24 antibody; Six transmembrane epithelial antigen of prostate antibody; Six transmembrane epithelial antigen of the prostate 1 antibody; Six transmembrane epithelial antigen of the prostate antibody; Six-transmembrane epithelial antigen of prostate 1 antibody; STEA1_HUMAN antibody; STEAP 1 antibody; Steap antibody; STEAP1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9UHE8

Immunogen:Recombinant Human Metalloreductase STEAP1 protein (3-69AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200

Background:E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. Probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis By similarity. Mediates \\\'Lys-63\\\'-linked polyubiquitination of TBK1, which probably participates in kinase activation.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:STEAP1

Research Areas:Epigenetics and Nuclear Signaling; Cancer; Tags & Cell Markers