STAM antibody , Cat. # FNab08283

SKU: FNab08283

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body(MVBs) when complexed with HGS(ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes.

Immunogen:signal transducing adaptor molecule(SH3 domain and ITAM motif) 1

Synonyms:STAM1

Observed MW:70 kDa

Uniprot ID:Q92783

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IF, IP

Recommended dilution:WB: 1:500-1:2000; IP: 1:200-1:1000; IF: 1:20-1:200

Gene ID:8027

Research Area:Epigenetics, Cardiovascular, Signal Transduction