ST5 Antibody - Cat. #: CSB-PA195797

SKU: CSB-PA195797

Size :100ul

Clone Number:

Aliases:DENND2B antibody; DENN domain containing protein 2B antibody; DENN domain-containing protein 2B antibody; DENN/MADD domain containing 2B antibody; HeLa tumor suppression 1 antibody; HTS1 antibody; p126 antibody; ST 5 antibody; ST5 antibody; ST5_HUMAN antibody; Suppression of tumorigenicity 5 antibody; Suppression of tumorigenicity 5 protein antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P78524

Immunogen:Synthesized peptide derived from internal of Human ST5.

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. May be involved in cytoskeletal organization and tumorogenicity. Isoform 1 seems to be involved in a signaling transduction pathway leading to activation of MAPK1/ERK2. Isoform 3 may block ERK2 activation stimulated by ABL1. Isoform 3 may alter cell morphology and cell growth.

Lichy J.H., Nucleic Acids Res. 24:4700-4708(1996).
Amid C., Cytogenet. Cell Genet. 93:284-290(2001).
Lichy J.H., Cell Growth Differ. 3:541-548(1992).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:ST5

Research Areas:Cancer;Signal transduction