SSRP1 Rabbit Polyclonal Antibody

SKU: BT-AP04909

Size:100μL

Background:The protein encoded by this gene is a subunit of a heterodimer that| along with SUPT16H| forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described| but its full-length nature is not known.

Research_area:Epigenetics and nuclear signaling

Target_protein:SSRP1

applications:WB

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:SSRP1

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):77990

UniProt accession:Human: Q08945; Mouse: Q08943; Rat: Q04931

Synonyms:SSRP1

GeneID:Human: 6749; Mouse: 20833; Rat: 81785