SSB antibody , Cat. # FNab08246

SKU: FNab08246

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.)

Background:The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus. Alternative promoter usage results in two different transcript variants which encode the same protein.

Immunogen:Sjogren syndrome antigen B (autoantigen La)

Synonyms:

Observed MW:47 kDa

Uniprot ID:P05455

Reactivity:Human

Tested Application:ELISA, WB, IHC

Recommended dilution:WB: 1:500 - 1:1000; IHC: 1:100 - 1:200

Gene ID:6741

Research Area:Metabolism