SRRM1 antibody , Cat. # FNab08242

SKU: FNab08242

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Part of pre-and post-splicing multiprotein mRNP complexes. Involved in numerous pre-mRNA processing events. Promotes constitutive and exonic splicing enhancer(ESE)-dependent splicing activation by bridging together sequence-specific(SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP(SNRP70 and SNRPA1) factors of the spliceosome. Stimulates mRNA 3'-end cleavage independently of the formation of an exon junction complex. Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. Binds RNA and DNA with low sequence specificity and has similar preference for either double-or single-stranded nucleic acid substrates.

Immunogen:serine/arginine repetitive matrix 1

Synonyms:SRM160

Observed MW:120-160 kDa

Uniprot ID:Q8IYB3

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB

Recommended dilution:WB: 1:500-1:2000

Gene ID:10250

Research Area:Neuroscience, Metabolism, Epigenetics