SPTA1 Antibody - Cat. #: CSB-PA966552

SKU: CSB-PA966552

Size :50ul

Clone Number:

Aliases:Alpha I spectrin antibody; EL 2 antibody; EL2 antibody; Elliptocytosis 2 antibody; Elliptocytosis2 antibody; Erythrocyte alpha spectrin antibody; erythrocyte antibody; Erythroid alpha spectrin antibody; Erythroid alpha-spectrin antibody; Erythroid spectrin alpha antibody; HPP antibody; HS3 antibody; Spectrin alpha chain antibody; Spectrin alpha chain erythrocyte antibody; Spectrin alpha erythrocytic 1 antibody; SPH3 antibody; SPTA 1 antibody; SPTA antibody; SPTA1 antibody; SPTA1_HUMAN antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P02549

Immunogen:Synthetic peptide of Human SPTA1

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:200-1:1000, IHC:1:25-1:100

Background:Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin, which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis type 2, pyropoikilocytosis, and spherocytic hemolytic anemia.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.05% sodium azide, 40% glycerol, pH7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:SPTA1

Research Areas: