SPP2A rabbit pAb

SKU: ES12985

Size: 100μL

Source:Rabbit

Applications:WB;IHC

Reactivity:Human; Mouse

Dilution:WB 1:500-2000;IHC-p 1:50-300

Immunogen:Synthesized peptide derived from human SPP2A AA range: 66-116

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):

Human_gene_id:84888

Human_swiss_prot_no:Q8TCT8

Subcellular_location:Late endosome membrane ; Multi-pass membrane protein . Lysosome membrane ; Multi-pass membrane protein . Membrane ; Multi-pass membrane protein ; Lumenal side . Colocalizes with palmitoylated and myristoylated proteins at the plasma membrane.

Other_name:

Background:This gene encodes a member of the GXGD family of aspartic proteases, which are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions, as well as a member of the signal peptide peptidase-like protease (SPPL) family. This protein is expressed in all major adult human tissues and localizes to late endosomal compartments and lysosomal membranes. A pseudogene of this gene also lies on chromosome 15. [provided by RefSeq, Feb 2012],