SORBS2 Polyclonal Antibody

SKU: E-AB-19081

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: SORBS2

Target Synonym: Arg binding protein 2;Arg-binding protein 2;Arg/Abl interacting protein 2;Arg/Abl interacting protein;Arg/Abl-interacting protein 2;ArgBP2;KIAA0777;PRO0618;sorbin and SH3 domain containing 2;Sorbin and SH3 domain-containing protein 2;Sorbin;Sorbs2;SRBS2

Research Areas: Signal transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: O94875

Accession:

Background: Arg and c-Abl represent the mammalian members of the Abelson family of non-receptor protein-tyrosine kinases. They interact with the Arg/Abl binding proteins via the SH3 domains present in the carboxy end of the latter group of proteins. This gene encodes the sorbin and SH3 domain containing 2 protein. It has three C-terminal SH3 domains and an N-terminal sorbin homology (SoHo) domain that interacts with lipid raft proteins. The subcellular localization of this protein in epithelial and cardiac muscle cells suggests that it functions as an adapter protein to assemble signaling complexes in stress fibers, and that it is a potential link between Abl family kinases and the actin cytoskeleton. Alternative splicing results in multiple transcript variants encoding different isoforms.

Concentration: 1.02 mg/mL

Immunogen: Fusion protein of human SORBS2

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: WB 1:1000-1:5000;IHC 1:150-1:300

Calculated MW: 124 kDa

ObservedMW: Refer to figures