SOCS6 antibody , Cat. # FNab08102

SKU: FNab08102

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate recognition component of a SCF-like ECS(Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins(By similarity). Regulates KIT degradation by ubiquitination of the tyrosine-phosphorylated receptor.

Immunogen:suppressor of cytokine signaling 6

Synonyms:CIS4, SOCS4

Observed MW:70 kDa

Uniprot ID:O14544

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IHC

Recommended dilution:WB: 1:500-1:2000; IHC: 1:20-1:200

Gene ID:9306

Research Area:Signal Transduction, Developmental biology