SNCB antibody , Cat. # FNab08062

SKU: FNab08062

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Non-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine(6OHDA)-stimulated caspase activation in a p53/TP53-dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA. Not found in the Lewy bodies associated with Parkinson disease.

Immunogen:synuclein, beta

Synonyms:Beta synuclein, SNCB, synuclein, beta, SYUB

Observed MW:14-18 kDa

Uniprot ID:Q16143

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IHC, IF, FC

Recommended dilution:WB: 1:500-1:1000; IP: 1:500-1:1000; IHC: 1:10-1:100; IF: 1:10-1:100

Gene ID:6620

Research Area:Neuroscience