SMUG1 Antibody, Biotin conjugated - Cat. #: CSB-PA706636LD01HU

SKU: CSB-PA706636LD01HU

Size :50ug

Clone Number:

Aliases:FDG antibody; HMUDG antibody; MGC104370 antibody; Single strand selective monofunctional uracil DNA glycosylase 1 antibody; Single strand selective monofunctional uracil DNA glycosylase antibody; Single-strand selective monofunctional uracil DNA glycosylase antibody; SMUG 1 antibody; Smug1 antibody; SMUG1 protein antibody; SMUG1_HUMAN antibody; UNG 3 antibody; UNG3 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q53HV7

Immunogen:Recombinant Human Single-strand selective monofunctional uracil DNA glycosylase protein (1-177AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Recognizes base lesions in the genome and initiates base excision DNA repair. Acts as a monofunctional DNA glycosylase specific for uracil (U) residues in DNA with a preference for single-stranded DNA substrates. The activity is greater toward mismatches (U/G) compared to matches (U/A). Excises uracil (U), 5-formyluracil (fU) and uracil derivatives bearing an oxidized group at C5 [5-hydroxyuracil (hoU) and 5-hydroxymethyluracil (hmU)] in ssDNA and dsDNA, but not analogous cytosine derivatives (5-hydroxycytosine and 5-formylcytosine), nor other oxidized bases. The activity is damage-specific and salt-dependent. The substrate preference is the following: ssDNA > dsDNA (G pair) = dsDNA (A pair) at low salt concentration, and dsDNA (G pair) > dsDNA (A pair) > ssDNA at high salt concentration.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:SMUG1

Research Areas:Epigenetics and Nuclear Signaling