SMG6 Antibody - Cat. #: CSB-PA773032LA01HU

SKU: CSB-PA773032LA01HU

Size :50ug

Clone Number:

Aliases:SMG6 antibody; C17orf31 antibody; EST1A antibody; KIAA0732Telomerase-binding protein EST1A antibody; EC 3.1.-.- antibody; EST1-like protein A antibody; Ever shorter telomeres 1A antibody; Smg-6 homolog antibody; Telomerase subunit EST1A antibody; hSmg5/7a antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q86US8

Immunogen:Recombinant Human Telomerase-binding protein EST1A protein (251-511AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background:Component of the telomerase ribonucleoprotein (RNP) complex that is essential for the replication of chromosome termini. May have a general role in telomere regulation. Promotes in vitro the ability of TERT to elongate telomeres. Overexpression induces telomere uncapping, chromosomal end-to-end fusions (telomeric DNA persists at the fusion points) and did not perturb TRF2 telomeric localization. Binds to the single-stranded 5\'-(GTGTGG)(4)GTGT-3\' telomeric DNA, but not to a telomerase RNA template component (TER).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:SMG6

Research Areas:Cancer