SIAH1 Rabbit Polyclonal Antibody

SKU: BT-AP04742

Size:100μL

Background:This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease| the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants| some encoding different isoforms and others that have not been fully characterized.

Research_area:Cell biology; Neuroscience

Target_protein:SIAH1

applications:WB

Reactivity:Human, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:SIAH1

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):31020

UniProt accession:Human: Q8IUQ4; Rat: Q920M9

Synonyms:SIAH1

GeneID:Human: 6477; Rat: 140941