SETD2 Monoclonal Antibody

SKU: BT-MCA4669

Size:100μL

Background:Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug 2008]

Research_area:Others

Target_protein:SETD2

applications:FCM

Reactivity:

Clonality:Monoclonal

Clone ID:4G11E6

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:SETD2

Immunogen:Purified recombinant fragment of human SETD2 (AA: 2054-2245) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):287.6kDa

UniProt accession:Q9BYW2

Synonyms:LLS, HYPB, SET2, HIF-1, HIP-1, KMT3A, HBP231, HSPC069, p231HBP

GeneID:29072