SESN3 Rabbit Polyclonal Antibody

SKU: BT-AP12615

Size:100μL

Background:This gene encodes a member of the sestrin family of stress-induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC-alpha serine/threonine-protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose| insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript variants.

Research_area:Cancer; Cardiovascular; Cell biology; Metabolism

Target_protein:SESN3

applications:WB

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:SESN3

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):54120

UniProt accession:Human: P58005; Mouse: Q9CYP7

Synonyms:SESN3

GeneID:Human: 143686; Mouse: 75747