SEN2 Polyclonal Antibody

SKU: BT-AP14114

Size:100μL

Background:This gene encodes one of the subunits of the tRNA splicing endonuclease. This endonuclease catalyzes the first step in RNA splicing which is the removal of introns. Mutations in this gene have been associated with pontocerebellar hypoplasia type 2. A pseudogene has been identified on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene.

Research_area:Epigenetics and nuclear signaling; Cell biology

Target_protein:TSEN2

applications:WB, ELISA

Reactivity:Human, Rat, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:tRNA-splicing endonuclease subunit Sen2

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: Q8NCE0; Mouse: Q6P7W5; Rat: Q5M954

Synonyms:tRNA-splicing endonuclease subunit Sen2 ;EC 3.1.27.9;tRNA-intron endonuclease Sen2;HsSen2

GeneID:Human: 80746