scn Antibody - Cat. #: CSB-PA858805HA01SKY

SKU: CSB-PA858805HA01SKY

Size :50ug

Clone Number:

Aliases:scn antibody; SA1754 antibody; Staphylococcal complement inhibitor antibody; SCIN antibody

Product Type:Polyclonal Antibody

Immunogen Species:Staphylococcus aureus (strain N315)

UniProt ID:Q99SU9

Immunogen:Recombinant Staphylococcus aureus Staphylococcal complement inhibitor protein (32-116AA)

Raised in:Rabbit

Species Reactivity:Staphylococcus aureus

Tested Applications:ELISA

Background:Involved in countering the first line of host defense mechanisms. Efficiently inhibits opsonization, phagocytosis and killing of S.aureus by human neutrophils. Acts by binding and stabilizing human C3 convertases (C4b2a and C3bBb), leading to their inactivation. The convertases are no longer able to cleave complement C3, therefore preventing further C3b deposition on the bacterial surface and phagocytosis of the bacterium. Also prevents C5a-induced neutrophil responses.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:scn

Research Areas:Others