SAMD8 Antibody, Biotin conjugated - Cat. #: CSB-PA822254LD01HU

SKU: CSB-PA822254LD01HU

Size :50ug

Clone Number:

Aliases:SAMD8Sphingomyelin synthase-related protein 1 antibody; SMSr antibody; EC 2.7.8.- antibody; Ceramide phosphoethanolamine synthase antibody; CPE synthase antibody; Sterile alpha motif domain-containing protein 8 antibody; SAM domain-containing protein 8 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q96LT4

Immunogen:Recombinant Human Sphingomyelin synthase-related protein 1 protein (1-152AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Sphingomyelin synthases synthesize sphingolipids through transfer of a phosphatidyl head group on to the primary hydroxyl of ceramide. SAMD8 is an endoplasmic reticulum (ER) transferase that has no sphingomyelin synthase activity but can convert phosphatidylethanolamine (PE) and ceramide to ceramide phosphoethanolamine (CPE) albeit with low product yield. Appears to operate as a ceramide sensor to control ceramide homeostasis in the endoplasmic reticulum rather than a converter of ceramides. Seems to be critical for the integrity of the early secretory pathway.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:SAMD8

Research Areas:Cancer; Cell biology; Metabolism; Signal transduction