S100A1 Polyclonal Antibody

SKU: AN006750L

Size::25μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:S100A1

Target Synonym:S100A;S100A1;Bpb;NEF;Protein S100-A1;S100;S100 alpha;S100 beta;S100 calcium binding protein A1;S100 calcium binding protein B;S100 calcium-binding protein A1;S-100 protein alpha chain;S100 protein alpha polypeptide;S-100 protein subunit alpha;S100-alpha;S100B;S100beta;S100A1

Research Areas:Neuroscience;Signal Transduction;Tags & Cell Markers

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Mouse

Application:WB

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P23297

Accession:

Background:Small calcium binding protein that plays important roles in several biological processes such as Ca2+ homeostasis, chondrocyte biology and cardiomyocyte regulation. In response to an increase in intracellular Ca2+ levels, binds calcium which triggers conformational changes .These changes allow interactions with specific target proteins and modulate their activity.Regulates a network in cardiomyocytes controlling sarcoplasmic reticulum Ca2+ cycling and mitochondrial function through interaction with the ryanodine receptors RYR1 and RYR2, sarcoplasmic reticulum Ca2+-ATPase/ATP2A2 and mitochondrial F1-ATPase. Facilitates diastolic Ca2+ dissociation and myofilament mechanics in order to improve relaxation during diastole.

Concentration:1 mg/mL

Immunogen:Recombinant Human S100A1 protein expressed by E.coli

Buffer:PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4

Purification method:Antigen Affinity Purification

Dilution:WB 1:250-1:500

Calculated MW:11 kDa

ObservedMW:12 kDa