S Antibody, FITC conjugated - Cat. #: CSB-PA333052LC01BJO

SKU: CSB-PA333052LC01BJO

Size :50ug

Clone Number:

Aliases:S antibody; 3 antibody; Spike glycoprotein antibody; S glycoprotein antibody; E2 antibody; Peplomer protein) [Cleaved into: Spike protein S1; Spike protein S2; Spike protein S2'] antibody

Product Type:Polyclonal Antibody

Immunogen Species:Bovine coronavirus

UniProt ID:P25194

Immunogen:Recombinant Bovine coronavirus Spike glycoprotein protein (326-540AA)

Raised in:Rabbit

Species Reactivity:Bovine coronavirus

Tested Applications:

Background:S1 attaches the virion to the cell membrane by binding to 9-O-acetylated sialic acid containing proteins, initiating the infection.By similarity S2 is a class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes (By similarity).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:S

Research Areas:Others