RYR1 Antibody, Biotin conjugated - Cat. #: CSB-PA020619LD01HU

SKU: CSB-PA020619LD01HU

Size :50ug

Clone Number:

Aliases:CCO antibody; Central core disease of muscle antibody; MHS antibody; MHS1 antibody; PPP1R137 antibody; Protein phosphatase 1 regulatory subunit 137 antibody; Ryanodine receptor 1 antibody; RYDR antibody; RYR antibody; RYR-1 antibody; RyR1 antibody; RYR1_HUMAN antibody; sarcoplasmic reticulum calcium release channel antibody; Skeletal muscle calcium release channel antibody; Skeletal muscle ryanodine receptor antibody; Skeletal muscle-type ryanodine receptor antibody; SKRR antibody; Type 1 ryanodine receptor antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P21817

Immunogen:Recombinant Human Ryanodine receptor 1 protein (1-534AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Calcium channel that mediates the release of Ca2+ from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering muscle contraction following depolarization of T-tubules. Repeated very high-level exercise increases the open probability of the channel and leads to Ca2+ leaking into the cytoplasm. Can also mediate the release of Ca2+ from intracellular stores in neurons, and may thereby promote prolonged Ca2+ signaling in the brain. Required for normal embryonic development of muscle fibers and skeletal muscle. Required for normal heart morphogenesis, skin development and ossification during embryogenesis

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:RYR1

Research Areas:Neuroscience; Cancer; Cardiovascular; Metabolism