RUNX1T1 Antibody - Cat. #: CSB-PA066534

SKU: CSB-PA066534

Size :50ul

Clone Number:

Aliases:Acute myelogenous leukemia 1 translocation 1 cyclin D related antibody; Acute myelogenous leukemia 1 translocation 1 protein antibody; AML1 MTG8 antibody; AML1T1 antibody; CBFA2T1 antibody; CDR antibody; Core binding factor runt domain alpha subunit 2 translocated to 1 antibody; Core binding factor runt domain alpha subunit 2 translocated to 1 cyclin D related antibody; Cyclin D related antibody; Cyclin D related protein antibody; Cyclin-D-related protein antibody; Eight twenty one protein antibody; ETO antibody; ETO protein antibody; MGC2796 antibody; MTG 8 antibody; MTG 8b antibody; MTG8 antibody; MTG8 protein antibody; MTG8_HUMAN antibody; MTG8b antibody; Myeloid translocation gene on 8q22 antibody; Protein CBFA2T1 antibody; Protein ETO antibody; Protein MTG 8 antibody; Protein MTG8 antibody; Runt related transcription factor 1 translocated to 1 (cyclin D related) antibody; Runt related transcription factor 1 translocated to 1 antibody; Runt related transcription factor 1 translocated to 1 cyclin D related antibody; RUNX1 translocation partner 1 antibody; RUNX1T1 antibody; Zinc finger MYND domain containing protein 2 antibody; Zinc finger MYND domain-containing protein 2 antibody; ZMYND 2 antibody; ZMYND2 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q06455

Immunogen:Synthetic peptide of Human RUNX1T1

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, IHC; ELISA:1:1000-1:2000, IHC:1:25-1:100

Background:This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:RUNX1T1

Research Areas:Epigenetics and Nuclear Signaling;Cancer